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Sioux Falls Research
CATARACT/LENS Studies
BVI Finevision
- Good Candidate: Subjects 22 years and older considering intraocular surgery to remove your cataracts
- About study: The purpose of the study is to evaluate the safety of the FINEVISION HP Trifocal IOL and how well it works compared to an FDA-approved intraocular lens
- Which eye: Both eyes
- How long is study: 12 months
- Number of visits: 11 visits
- Cost to the patient: The study visits, study IOLs and study-related procedures, other than your cataract surgery, will be provided at no cost to you or your insurance company.
- Compensation: Up to $550 for completed visits
- Co-management: None
- Sioux Falls Lead Contact: Elle Malmanger elle.malmanger@vancethompsonvision.com 605-361-7083
RxSight 029
- Good Candidate: Subjects Age between 40 and 80 with cataracts affecting their vision
- About Study: The purpose of this study is to further evaluate the safety of an approved intra-ocular lens (IOL) called RxSight Light Adjustable Lens (LAL) and a device called Light Delivery Device (LDD)
- Which eye: OD or OS, randomized
- How long is study: 6 months
- How many visits: 7 visits for control group and up to 12 for LAL group
- Cost to patient/financial: standard cataract surgery billed to insurance, all study related exams and procedures are no additional cost (i.e. LAL LDD treatments and lock-ins)
- Compensation: $450 total, no mileage, fine tune included
- Co-management: none
- Sioux Falls Lead coordinator: Rebekah Tuchscherer rebekah.tuchscherer@vancethompsonvision.com 605-705-3517
- Sioux Falls Secondary coordinator: Gabrielle Malmanger elle.malmanger@vancethompsonvision.com 605-371-7083
GLAUCOMA RESEARCH
None at this time.
PRESBYOPIC RESEARCH
Ocuphire Presbyopis OPI-NYPX-301
- Good Candidate: Subjects 40 to 64 years old presbyopic patients with generally healthy eyes
- About study: The purpose of the study is to evaluate the safety and efficacy of Nyxol (POS 0.75%) and the combination of Nyxol (POS 0.75%) and LDP 0.4% in subjects with presbyopia. Subjects will be given study randomized eye drops to take in both eyes every night. There will be 4 all day study visits that last 8-9 hours.
- Which eye: Both eyes
- How long is study: 22-36 days
- Number of visits: 5 visits
- Cost to the patient: None
- Compensation: $1,035
- Co-management: None
- Sioux Falls Lead Contact: Allie Winter 605-371-7077
Santen
- Good Candidate: Persons between the ages of 47- 55 years with a diagnosis of Presbyopia in both eyes.
- About Study: The purpose of this clinical study is to determine how safe and effective this investigational study drug (eye drop) is, and to see how well it works to treat Presbyopia
- Which eye: both eyes
- How long is the study: 3 months
- How many visits: 7 visits
- Cost to patient: No cost to patient
- Compensation: Up to $875 ($125 per completed visit)
- Co-management: No Co-management
- Lead Contact: Elle Malmanger elle.malmanger@vancethompsonvision.com 605-371-7083
VISUS Therapeutics, Inc. VT-003
- Good Candidate: Persons between 45 and 80 years of age and have been diagnosed with presbyopia.
- About Study: The purpose of this study is to assess the safety of the study drug, BRIMOCHOLTM PF and Carbachol PF, and their efficacy (whether it works) in people with presbyopia.
- Which eye: Both eyes
- How long is study: 1 years
- How many visits: 6 visits
- Cost to patient: No additional costs. You and/or your insurance may be responsible for any routine/standard procedures which are not part of the study.
- Compensation: Up to $1,560.00 for completed visits.
- Co-management: No co-management
- Sioux Falls Lead Contact : Jason Meyer jason.meyer@vancethompsonvision.com 605-371-7064
CORNEA RESEARCH
CloudBreak CBT-CS301 Pterygium Study
- Good Candidate: persons 12 and above with primary or recurrent pterygium, who are otherwise in generally good health
- About Study: The main purpose of this study is to look at how safe the study drug, CBT-001 ophthalmic emulsion, is and whether it works to treat pterygium.
- Which eye: One or both eyes but only one eyes must meet all criteria
- How long is study: 2 years
- How many visits: 12, not including unscheduled visits
- Cost to patient: No cost to the patient
- Compensation:
- Co-management: No co-management
- Sioux Falls Lead Contact: A’lece Mathison alece.mathison@vancethompsonvision.com
Glaukos Crosslinking GLK-202-02
- Good Candidate: Patients diagnosed with keratoconus in one or both eyes
- About Study: Subjects are treated with either epi-on cross-linking or sham and are followed for one year. At one year, subjects are treated with the opposite treatment and are followed for 6 months.
- Which eye: One eye or both eyes can be enrolled in this study
- How long is study: About 20 months
- How many visits: 16
- Cost to patient: Patients are responsible for the cost of the post-op medication
- Compensation: $1600 - $3200 ($100 for each visit completed per eye enrolled)
- Co-management: No Co-management
- Lead Contact: Jason Meyer jason.meyer@vancethompsonvision.com 605-371-7064
TreFoil TTHX-901 (Fuchs' Dystrophy)
Good Candidate: Three options;
Patient with ocular condition that could benefit from TTHX1114 injections
Cataract patient at high-risk of corneal edema following CAT surgery
- Patient with FECD scheduled for DSO
**Fellow eye must have 20/100 or better for all three options
- About Study: open-label, evaluate safety/efficacy of TTHX1114
- Which eye: One eye
- How long is study: 3 months for options 1 & 2, 1 year for option 3
- How many visits: 7-11
- Cost to patient: Injections are free, CAT surgery billed to insurance
- Compensation: $525-625
- Co-management: No Co-management
- Sioux Falls Lead Contact: Rebekah Tuchscherer rebekah.tuchscherer@vancethompsonvision.com 605-705-3517
Claris CSB-C20-003
- Good Candidate: Subjects 18 years of age and older who have been diagnosed with stage 2 (persistent epithelial defect) or stage 3 (corneal ulcer) Neurotrophic Keratitis (NK)
- About Study: The purpose of this study is to compare the safety and effectiveness of the study product, CSB.001 ophthalmic solution 0.1% to placebo when treating stage 2 and 3 Neurotrophic Keratitis.
- Which eye: One eye. Study eye determined by your Dr.
- How long is study: 2 phases. 8-10 weeks per phase.
- How many visits: 2 phases, 9-10 visits per phase. Not all subjects will complete both phases
- Cost to patient: No cost to patient
- Compensation: up to $2000 for completed visits. (up to $1000 per phase), mileage compensation up to $250/visit if over 50 miles round trip
- Co-management: No Co-management
- Lead Contact: Brandon Joffer brandon.joffer@vancethompsonvision.com 605-361-7083
REFRACTIVE RESEARCH
STAAR CP-022 EVO/EVO-ICL
- Good Candidate: Subject 21 - 45 years old with Myopia ranging from -3.00 D to ≤ -20.00 D spherical equivalent, Up to 4.00 D of astigmatism, Anterior chamber depth 3.00 mm or more, generally healthy eyes.
- About Study: Post-approval study assessing the rate of early IOP increases after EVO/EVO+ICL implantation
- Which eye: Both eyes
- How long is study: 2-3 weeks
- How many visits: 7 visits
- Cost to patient: Patient pays $500 per eye, $1000 total
- Compensation: None
- Co-management: No co-management.
- Lead Contact: A’Lece Mathison, alece.mathison@vancethompsonvision.com 605-371-7049
Bausch and Lomb 906 Hyperopic LASIK
- Good Candidate: At least 22 years old with hyperopia. Sphere range +1.00 D to +4.00 D with or without cylinder up to +2.00 D and max MRSE of +5.00 D. Stable refraction (change of less than or equal to +/- 0.50 D in MRSE) for at least 12 months. UCDVA 20/40 or worse. Pupil size less than 7.0mm.
- About Study: A Study to Investigate the Safety and Effectiveness of the TENEO 317 Model 2 (1.28 US) Excimer Laser for Laser In Situ Keratomileusis (LASIK) Surgery to Treat Hyperopia With or Without Astigmatism
- Which eye: Both eyes - must agree to emmetropia in both eyes
- How long is study: 1 year
- How many visits: 9 visits over 12 months.
- Cost to patient: Procedure is performed at no cost to patient.
- Compensation: Subject will be compensated up to $480.00, in addition to free LASIK.
- Co-management: No co-management.
- Lead Contact: Brandon Joffer brandon.joffer@vancethompsonvision.com 605-371-7068
Alcon Contura LASIK - IIT
- Good Candidate: Age 21-38 with myopia up to -8.00 D, with or without cylinder up to 3.00 D, and are eligible for Contura (topo-guided) LASIK. Max treated MRSE: -9.00 D.About Study: Comparison of visual acuity and quality of life following Contoura with Phorcides compared to WaveLight Wavefront Optimized LASIK.
- Which eye: Both eyes
- How many visits: 2 visits
- Cost to patient: Patient is responsible for all costs associated with LASIK surgery.
- Compensation: Patient receives $250 after returning for a 3-Month visit.
- Co-management: Patients can do post-operative care where they prefer.
- Contacts: Sioux Falls Lead Contact: Jason Meyer jason.meyer@vancethompsonvision.com 605-371-7064
MISCELLANEOUS~DROPS & HEALTHY EYES
None at this time
Fargo Research
CATARACT/LENS Studies
BVI Finevision - In Follow up
PRESBYOPIC
VISUS Therapeutics, Inc. VT-003
Good Candidate: Persons between 45 and 80 years of age and have been diagnosed with presbyopia.- About Study: The purpose of this study is to assess the safety of the study drug, BRIMOCHOLTM PF and Carbachol PF, and their efficacy (whether it works) in people with presbyopia.
- Which eye: Both eyes
- How long is study: 1 years
- How many visits: 6 visits
- Cost to patient: No additional costs. You and/or your insurance may be responsible for any routine/standard procedures which are not part of the study.
- Compensation: Up to $1,560.00 for completed visits.
- Co-management: No co-management
- Fargo Lead Contact : Alyson Saville alyson.saville@vancethompsonvision.com 701-809-9905
CORNEA RESEARCH
Avedro Cross Linking ACP-KXL-401
- Good Candidate: at least 18 years of age, have corneal ectasia after refractive surgery (such as LASIK, PRK, and planning to have corneal collagen cross-linking, or had cross-linking within the past 90 days.
- About Study: You may be eligible to take part in this observational registry study because you have been diagnosed with corneal ectasia after refractive surgery (such as LASIK or PRK) and you are planning, or have had, corneal collagen cross-linking procedure performed
- Which eye: One or both eyes
- How long is study: 3 years
- How many visits: 5-7 visits over 36 months. (subjects may enroll at month 3)
- Cost to patient: You or your medical insurance company may be required to pay up to $6,750.00 for the cost of the treatment, medications prescribed by the study doctor during the course of the study, and for any additional standard medical care given during this research study.
- Compensation: Subject will be compensated up to $600.00.
- Co-management: No co-management
- Fargo Lead Contact: Sarah Thiede sarah.thiede@vancethompsonvision.com 701-639-2017
REFRACTIVE
Alcon Contura LASIK - IIT
- Good Candidate: Age 21-38 with myopia up to -8.00 D, with or without cylinder up to 3.00 D, and are eligible for Contura (topo-guided) LASIK. Max treated MRSE: -9.00 D.
- About Study: Comparison of visual acuity and quality of life following Contoura with Phorcides compared to WaveLight Wavefront Optimized LASIK.
- Which eye: Both eyes
- How long is study: 3 months
- How many visits: 2 visits
- Cost to patient: Patient responsible for all costs associated with LASIK surgery.
- Compensation: Patient receives $250 after returning for a 3-Month visit.
- Co-management: Patients can do post-operative care where they prefer.
- Contacts: Fargo Lead Contact: Laida Zimmel laida.zimmel@vancethompsonvision.com 701-566-5628
MISCELLANEOUS~DROPS & HEALTHY EYES
None at this time
BOZEMAN RESEARCH
CATARACT/LENS Studies
Studies in follow-up
CORNEA RESEARCH
Glaukos Crosslinking GLK-202-02
- Good Candidate: Patients diagnosed with keratoconus in one or both eyes
- About Study: Subjects are treated with either epi-on cross-linking or sham and are followed for one year. At one year, subjects are treated with the opposite treatment and are followed for 6 months.
- Which eye: One eye or both eyes can be enrolled in this study
- How long is study: About 20 months
- How many visits: 16
- Cost to patient: Patients are responsible for the cost of the post-op medication
- Compensation: $1600 - $3200 ($100 for each visit completed per eye enrolled)
- Co-management: No Co-management
- Lead Contact: Briana Wolfe briana.wolfe@vancethompsonvision.com
Avedro Cross Linking ACP-KXL-401
- Locations: Fargo, Bozeman
- Good Candidate: at least 18 years of age, have corneal ectasia after refractive surgery (such as LASIK, PRK, and planning to have corneal collagen cross-linking, or had cross-linking within the past 90 days.
- About Study: You may be eligible to take part in this observational registry study because you have been diagnosed with corneal ectasia after refractive surgery (such as LASIK or PRK) and you are planning, or have had, corneal collagen cross-linking procedure performed
- Which eye: One or both eyes
- How long is study: 3 years
- How many visits: 5-7 visits over 36 months. (subjects may enroll at month 3)
- Cost to patient: You or your medical insurance company may be required to pay up to $6,750.00 for the cost of the treatment, medications prescribed by the study doctor during the course of the study, and for any additional standard medical care given during this research study.
- Compensation: Subject will be compensated up to $600.00.
- Co-management: No co-management
- Bozeman Lead Contact: Briana Wolfe briana.wolfe@vancethompsonvision.com 406-219-0344
REFRACTIVE
Alcon Contura LASIK - IIT
- Good Candidate: Age 21-38 with myopia up to -8.00 D, with or without cylinder up to 3.00 D, and are eligible for Contura (topo-guided) LASIK. Max treated MRSE: -9.00 D.
- About Study: Comparison of visual acuity and quality of life following Contoura with Phorcides compared to WaveLight Wavefront Optimized LASIK.
- Which eye: Both eyes
- How long is study: 3 months
- How many visits: 2 visits
- Cost to patient: Patient responsible for all costs associated with LASIK surgery.
- Compensation: Patient receives $250 after returning for a 3-Month visit.
- Co-management: Patients can do post-operative care where they prefer
- Contacts: Bozeman Lead Contact: Briana Wolfe briana.wolfe@vancethompsonvision.com
Omaha Research
CATARACT/LENS Studies
RxSight 029
- Good Candidate: Subjects Age between 40 and 80 with cataracts affecting their vision
- About Study: The purpose of this study is to further evaluate the safety of an approved intra-ocular lens (IOL) called RxSight Light Adjustable Lens (LAL) and a device called Light Delivery Device (LDD)
- Which eye: OD or OS, randomized
- How long is study: 6 months
- How many visits: 7 visits for control group and up to 12 for LAL group
- Cost to patient/financial: standard cataract surgery billed to insurance, all study related exams and procedures are no additional cost (i.e. LAL LDD treatments and lock-ins)
- Compensation: $450 total, no mileage, fine tune included
- Co-management: none
- Omaha Lead Coordinator: Sarah Hartnett sarah.hartnett@vancethompsonvision.com 402-899-8020
BVI Finevision
- Good Candidate: Subjects 22 years and older considering intraocular surgery to remove your cataracts
- About study: The purpose of the study is to evaluate the safety of the FINEVISION HP Trifocal IOL and how well it works compared to an FDA-approved monocular IOL.
- Which eye: Both eyes
- How long is study: 12 months
- Number of visits: 11 visits
- Cost to the patient: The study visits, study IOLs and study-related procedures, other than your cataract surgery, will be provided at no cost to you or your insurance company.
- Compensation: Up to $550 for completed visits
- Co-management: None
- Omaha Lead Contact : Sarah Hartnett sarah.hartnett@vancethompsonvision.com 402-899-8020
Refractive Studies
Alcon Contura LASIK - IIT
- Good Candidate: Age 21-38 with myopia up to -8.00 D, with or without cylinder up to 3.00 D, and are eligible for Contura (topo-guided) LASIK. Max treated MRSE: -9.00 D.
- About Study: Comparison of visual acuity and quality of life following Contoura with Phorcides compared to WaveLight Wavefront Optimized LASIK.
- Which eye: Both eyes
- How long is study: 3 months
- How many visits: 2 visits
- Cost to patient: Patient responsible for all costs associated with LASIK surgery.
- Compensation: Patient receives $250 after returning for a 3-Month visit.
- Co-management: Patients can do post-operative care where they prefer.
- Omaha Lead Contact: Amanda amanda.aparo@vancethompsonvision.com
Cornea Research
Glaukos Crosslinking GLK-202-02
- Good Candidate: Between 12 and 55 years old
- Maximum corneal curvature, as measured by Kmax of ≥ 47.00 D
- Shows progression within 18 months when comparing either…
- An increase of ≥ 1.00 D in Kmax or simK;
- An increase of ≥ 1.00 D in regular astigmatism on subjective manifest refraction
- A myopic shift (towards greater negative sphere) of 0.50 D or more on subjective manifest refraction
BCDVA of 20/20 or worse
No previous corneal surgery or other corneal disease
- About Study: The objectives of this study are to evaluate the safety and efficacy of epithelial-on corneal collagen cross-linking (CXL) in slowing down the progression of, and/or reducing maximum corneal curvature in eyes with keratoconus
- Which eye: can be OU or monocular
- How long is study: 18 Months
- How many visits: 16
- Cost to patient: procedure is free (not run through insurance), pt pays for postop drops
- Compensation: $100 per completed visit
- Co-management: No Co-management
- Omaha Lead contact: Bethany Dudley bethany.dudley@vancethompsonvision.com 402-899-8020
Alexandria Research
CATARACT/LENS Studies
BVI Finevision
- Good Candidate: Subjects 22 years and older considering intraocular surgery to remove your cataracts
- About study: The purpose of the study is to evaluate the safety of the FINEVISION HP Trifocal IOL and how well it works compared to an FDA-approved intraocular lens
- Which eye: Both eyes
- How long is study: 12 months
- Number of visits: 11 visits
- Cost to the patient: The study visits, study IOLs and study-related procedures, other than your cataract surgery, will be provided at no cost to you or your insurance company.
- Compensation: Up to $550 for completed visits
- Co-management: None
- Alexandria Lead Contact: Abby Garofalo abby.garofalo@vancethompsonvision.com 320-391-905
RX SIGHT 029
- Good Candidate: Subjects Age between 40 and 80 with cataracts affecting their vision
- About Study: The purpose of this study is to further evaluate the safety of an approved intra-ocular lens (IOL) called RxSight Light Adjustable Lens (LAL) and a device called Light Delivery Device (LDD)
- Which eye: OD or OS, randomized
- How long is study: 6 months
- How many visits: 7 visits for control group and up to 12 for LAL group
- Cost to patient/financial: standard cataract surgery billed to insurance, all study related exams and procedures are no additional cost (i.e. LAL LDD treatments and lock-ins)
- Compensation: $450 total, no mileage, fine tune included
- Co-management: none
- Alexandria Lead coordinator: Abby Garofalo abby.garofalo@vancethompsonvision.com 320-335-2973
GLAUCOMA STUDIES
No studies at this time
Cornea Research
Glaukos Crosslinking GLK-202-02
- Good Candidate: Between 12 and 55 years old
- Maximum corneal curvature, as measured by Kmax of ≥ 47.00 D
- Shows progression within 18 months when comparing either…
- An increase of ≥ 1.00 D in Kmax or simK;
- An increase of ≥ 1.00 D in regular astigmatism on subjective manifest refraction
- A myopic shift (towards greater negative sphere) of 0.50 D or more on subjective manifest refraction
BCDVA of 20/20 or worse
No previous corneal surgery or other corneal disease
- About Study: The objectives of this study are to evaluate the safety and efficacy of epithelial-on corneal collagen cross-linking (CXL) in slowing down the progression of, and/or reducing maximum corneal curvature in eyes with keratoconus
- Which eye: can be OU or monocular
- How long is study: 18 Months
- How many visits: 16
- Cost to patient: procedure is free (not run through insurance), pt pays for postop drops
- Compensation: $100 per completed visit
- Co-management: No Co-management
- Alexandria Lead Contact:Miranda Danielson miranda.danielson@vancethompsonvision.com 320-335-2971